Publications by authors named "E Helden"

Background: Increasing evidence supports a positive relationship between the intensity of early postoperative pain, and the risk of 30-day postoperative complications. Higher pain levels may hamper recovery and contribute to immunosuppression after surgery. This leaves patients at risk of postoperative complications.

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Background: Guidelines do not provide clear recommendations with regard to the use of low intra-abdominal pressure (IAP) during laparoscopic surgery. The aim of this meta-analysis is to assess the influence of low versus standard IAP during laparoscopic surgery on the key-outcomes in perioperative medicine as defined by the StEP-COMPAC consensus group.

Materials And Methods: We searched the Cochrane Library, PubMed, and EMBASE for randomized controlled trials comparing low IAP (<10 mmHg) with standard IAP (10 mmHg or higher) during laparoscopic surgery without time, language, or blinding restrictions.

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Article Synopsis
  • Minimally invasive adrenalectomy is commonly performed for small adrenal tumors, but this study focuses on the prevalence of chronic postsurgical pain, which hasn't been extensively researched before.
  • A total of 602 patients underwent the surgery between 2007 and 2019, with 14.9% experiencing chronic pain afterward, and 33% of those with pain also reported localized hypoesthesia (reduced sensation).
  • Young age emerged as a notable risk factor for chronic pain, and patients experiencing this pain reported a significantly lower quality of life compared to those without pain.*
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Study Objective: To assess whether different intensities of intra-abdominal pressure and deep neuromuscular blockade influence the risk of intra-operative surgical complications during laparoscopic donor nephrectomy.

Design: A pooled analysis of ten previously performed prospective randomized controlled trials.

Setting: Laparoscopic donor nephrectomy performed in four academic hospitals in the Netherlands: Radboudumc, Leiden UMC, Erasmus MC Rotterdam, and Amsterdam UMC.

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