Health-Related Behaviour Clusters and Functional Dentition in Older People.

Objectives: To identify different clusters of health-related behaviours and examine whether these clusters are associated with maintaining 20 or more teeth.

Background: Engaging in risky behaviours impacts tooth loss, particularly among older adults. Maintaining 20 teeth is a challenge for this age group.

snRNA-seq stratifies multiple sclerosis patients into distinct white matter glial responses.

Poor understanding of the cellular and molecular basis of clinical and genetic heterogeneity in progressive multiple sclerosis (MS) has hindered the search for new effective therapies. To address this gap, we analyzed 632,000 single-nucleus RNA sequencing profiles from 156 brain tissue samples of MS and control donors to examine inter- and intra-donor heterogeneity. We found distinct cell type-specific gene expression changes between MS gray and white matter, highlighting clear pathology differences.

A survey of foundation dentists' experiences of clinical audit.

Introduction Clinical audit is one of the central pillars of clinical governance and is a valuable quality improvement tool. Clinical audit has benefits for all stakeholders and provides evidence of compliance with the requirements of the UK statutory regulatory bodies. The levels of knowledge, experience and understanding of clinical audit of recent UK graduates is variable.

Health risk assessment of aflatoxin M1 exposure through traditional dairy products in Fasa, Iran.

Milk and dairy products are an important source of essential nutrients for human health. However, contamination of these foods poses a significant public health concern. In this study, risk assessment of aflatoxin M1 (AFM1) exposure associated with the consumption of traditional milk and dairy products in Fasa, Fars Province, Iran, was carried out.