Publications by authors named "E Hauzenberger"

Article Synopsis
  • Enterovirus D68 (EV-D68) infections can cause severe respiratory issues and acute flaccid myelitis, with a significant rise reported during the fall-winter season of 2021-2022 across Europe.
  • The study by the European Non-Polio Enterovirus Network (ENPEN) analyzed over 10,481 samples from 19 countries, identifying 1,004 as EV-D68, predominantly affecting young children, where 37.9% required hospitalization.
  • Additionally, genetic analyses uncovered two new B3-derived lineages without regional patterns, indicating a notable impact of the infections and the emergence of new virus strains.
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A previously healthy male patient had detectable monkeypox virus DNA in saliva 76 days after laboratory confirmation of infection. A comprehensive characterization of viral kinetics and a detailed follow-up indicated a declining risk for transmission during the weeks after monkeypox symptoms appeared.

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Picornaviruses (family Picornaviridae) are small, nonenveloped, positive-sense, single-stranded RNA viruses. The members of this family are currently classified into 47 genera and 110 species. Of picornaviruses, entero- and parechoviruses are associated with aseptic meningitis.

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Article Synopsis
  • An outbreak of pseudocowpox virus (PCPV) affected a dairy herd of about 80 cows, with 90% of them displaying skin lesions primarily on the vulva and vaginal mucosa.
  • Histological examinations revealed a viral infection, confirmed by electron microscopy showing parapoxvirus particles and deep sequencing identifying the PCPV strain VR 634.
  • The study ruled out other causes for the symptoms, such as bovine herpesvirus 1, and suggested that a rolling cow brush might have facilitated the virus's transmission.
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Article Synopsis
  • The study investigates the structural characteristics of the synaptic vesicle protein 2A (SV2A), which is important for the anti-epileptic drug levetiracetam (LEV), using Protein Tomography on mouse brain tissue.
  • Two main shapes of SV2A were identified: a compact funnel with a pore-like opening and a V-shaped structure with a cleft, indicating the protein's high flexibility and potential valve-like function.
  • The findings suggest that LEV binding does not significantly change the SV2A structure, and the research provides new structural insights that support its function as a transporter, similar to other known transporter proteins.
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