Publications by authors named "E Haslett"
Anti-CD117 monoclonal antibody (mAb) agents have emerged as exciting alternative conditioning strategies to traditional genotoxic irradiation or chemotherapy for both allogeneic and autologous gene-modified hematopoietic stem cell transplantation. Furthermore, these agents are concurrently being explored in the treatment of mast cell disorders. Despite promising results in animal models and more recently in patients, the short- and long-term effects of these treatments have not been fully explored.
View Article and Find Full Text PDFBackground: Training programmes for obstetrics and gynaecology (O&G) and general surgery (GS) vary significantly, but both require proficiency in laparoscopic skills. We sought to determine performance in each specialty.
Design: Prospective, observational study.
Article Synopsis
- The study investigates the link between pre-eclampsia and pre-existing cardiac dysfunction in pregnant women, finding no significant increase in overall pre-eclampsia rates.
- A modest rise in cases of preterm pre-eclampsia and a significant increase in fetal growth restriction (FGR) were observed among women with cardiac issues.
- The findings suggest that while there are concerns regarding pregnancy outcomes in this group, the relationship between cardiac dysfunction and pre-eclampsia is not clearly causal, and the use of β-blockers may have an impact on birthweight.
We present a rare case of Coombs-negative autoimmune haemolytic anaemia in a multiparous woman in secondary care. There were no known underlying medical or obstetric risk factors for haemolytic anaemia. Following extensive investigation and a therapeutic trial of oral corticosteroids, a diagnosis was made.
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