Publications by authors named "E Hardy"

Syphilis, once in decline, is seeing a rapid re-emergence throughout the United States. A sexually transmitted infection caused by the spirochete Treponema pallidum, syphilis infection in pregnancy can result in serious complications and have a profound impact on maternal and neonatal health. As rates of syphilis have increased among people of reproductive age, so too have cases of congenital syphilis.

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Reward processing involves evaluation of stimuli to inform what an individual works to pursue or avoid. Patients with behavioral variant frontotemporal dementia (bvFTD) often display reward processing changes, including insensitivity to aversive stimuli. It is unknown how early in the disease course reward changes are detectable.

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Article Synopsis
  • The study investigates how reward perception changes in patients with behavioral variant frontotemporal dementia (bvFTD), focusing on olfactory rewards like food and alcohol.
  • It found that stronger positive feelings towards these odors were linked to better connectivity between the ventral pallidum and areas of the brain associated with reward processing, specifically the anterior cingulate cortex and ventromedial prefrontal cortex.
  • Additionally, the research revealed that atrophy in the anterior cingulate cortex affected these perceptions, suggesting that both structural damage and connectivity within reward-related brain regions play vital roles in how pleasant olfactory stimuli are perceived in bvFTD patients.
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Article Synopsis
  • * It includes recommendations for using the anti-SARS-CoV-2 neutralizing antibody pemivibart as pre-exposure prophylaxis based on systematic review evidence.
  • * The guidelines follow GRADE methodology for assessing evidence certainty and strength of recommendations, and pemivibart is included in the FDA's Emergency Use Authorization.
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Poor glucose regulation associated with gradual insulin resistance is a significant risk factor in several age-related chronic diseases. An eating plan that promotes a lower carbohydrate intake may have a beneficial effect on glucose metabolism. This study aimed to evaluate how a diet reduced in carbohydrate by 32% (RCHO) over a 2 month period would influence the metabolic profile of older individuals ( = 24) living in a retirement home (RH).

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