Publications by authors named "E Hardak"
Article Synopsis
- Yellow Nail Syndrome (YNS) is a rare condition marked by yellow, malformed nails, swelling due to lymphedema, and chronic lung issues, typically presenting in adulthood, with potential genetic links suggested.
- Researchers conducted genetic sequencing and expression studies on 11 patients (6 with congenital YNS and 5 with sporadic YNS) to investigate its underlying causes.
- Findings revealed biallelic variants in genes related to the Wnt/planar cell polarity pathway in congenital cases, indicating that defects in cellular organization could be key to understanding YNS's development, though the study's small sample size is a limitation.
Introduction: Systemic sclerosis is a complex disease that affects various target organs, making it difficult to assess response and determine remission or relapse. A baseline Neutrophil-to-Lymphocyte Ratio (NLR) >2.95 is associated with severe progressive skin and lung disease and decreased 5-year survival in systemic sclerosis (SSc).
View Article and Find Full Text PDFArticle Synopsis
- The study investigates the role of the genioglossus (GG) muscle in tongue movement during breathing, specifically focusing on the anterior fibers and their EMG activity during wakefulness and sleep.
- Results showed that electrical stimulation of the anterior GG fibers caused tongue retraction, while the longitudinal fibers were responsible for protrusion.
- The findings reveal distinct control mechanisms for the anterior GG compared to the protrusive fibers, suggesting that treatments for obstructive sleep apnea should avoid stimulating the retractor fibers of the GG.
Von Willebrand factor: a possible biomarker for disease activity in vasculitis.
Scand J Rheumatol
November 2024
Objective: Inflammation markers, e.g. C- reactive protein (CRP) and sedimentation rate, can be normal despite active vasculitis.
View Article and Find Full Text PDF