Selective IgM deficiency: evaluation of 75 patients according to different diagnostic criteria.

Selective IgM deficiency (SIgMD) has recently been included in the inborn errors of immunity classification. SIgMD has conflicting diagnostic criteria and diverse clinical and immunological findings. We aimed to assess the clinical and laboratory profiles of patients with SIgMD and to compare the data of patients diagnosed using two inclusion criteria.

Not all Costs Are Created Equal: What Are the Types of Costs and Why Do They Matter?

Value-based care models are health care economic frameworks that aim to prioritize and financially incentivize quality of care, provider performance, and patient experience. The focus on value-based care metrics will undoubtedly lead to a greater weight placed on economic analyses in arthroplasty. Authors of cost analyses in arthroplasty often use the term "cost" in ways that have vastly different underlying meanings.

Predictive Value of V̇O in Adult Congenital Heart Disease in Comparison with Heart Failure with Reduced Ejection Fraction.

Background: Peak oxygen consumption (V̇O ) is used to predict outcomes and the timing of transplantation in patients with heart failure with reduced ejection fraction (HFrEF); V̇O also has predictive utility in patients with adult congenital heart disease (ACHD). However, the predictive value of a given V̇O in patients with ACHD compared to those with HFrEF, especially after adjustment for age and sex, is not clear.

Methods: To address this, we performed a longitudinal cohort study comparing patients with ACHD to patients with HFrEF.

The Attitudes, Beliefs and Perspectives of Registered Nurses on Sleep Health Management in Residential Aged Care Facilities: A Qualitative Study.

Aim: To explore the attitudes, beliefs and perspectives of registered nurses (RNs) regarding sleep health and sleep health management of residents living in aged care settings in Australia.

Design: Qualitative inductive thematic analysis of semi-structured interviews.

Methods: Semi-structured interviews were conducted with RNs working in residential aged care facilities using a topic guide between August 2021 and April 2022.

Molecular and agro-morphological diversity assessment of some bread wheat genotypes and their crosses for drought tolerance.

Wheat, a staple cereal crop, faces challenges due to climate change and increasing global population. Maintaining genetic diversity is vital for developing drought-tolerant cultivars. This study evaluated the genetic diversity and drought response of five wheat cultivars and their corresponding F1 hybrids under well-watered and drought stress conditions.