Publications by authors named "E Halvorsen"

Article Synopsis
  • Ventricular septal rupture (VSR) is a rare but serious complication after heart attacks, and its symptoms can vary widely, highlighting the need for careful clinical evaluation.
  • A middle-aged man with no prior heart issues experienced heart failure symptoms while abroad; tests revealed a small area of heart damage, but it wasn't initially linked to a major heart condition.
  • Ultimately, he was diagnosed with a large VSR after further investigations showed a significant defect, leading to successful surgical repair, emphasizing that VSR can occur even after minor heart events and that new heart murmurs should not be overlooked.
View Article and Find Full Text PDF

Background: Although fecal microbiota transplant has been used to prevent recurrent Clostridioides difficile infection (rCDI), documented pathogen transmissions highlight inherent safety risks of minimally processed stool. We describe manufacturing processes for fecal microbiota spores, live (VOWST; VOS, formerly SER-109), a microbiota-based oral therapeutic of Firmicutes spores.

Methods: Bacterial inactivation kill curves were obtained after ethanol exposure for 4 model organisms spiked into process intermediates.

View Article and Find Full Text PDF
Article Synopsis
  • Silicon-based kinetic energy converters, or electrostatic vibration energy harvesters, aim to generate power for IoT devices but struggle with low-frequency vibrations typical in applications like wearables and monitoring.
  • Traditional designs fail to produce enough power due to their narrow operational frequency range and low-frequency ambient vibrations.
  • The study introduces an impact-based harvester that uses electrode collisions to generate high-frequency oscillations, enhancing energy conversion and allowing the device to operate effectively across a broader frequency spectrum, up to 700 Hz.
View Article and Find Full Text PDF

The main challenge addressed in this paper is how to handle and recycle the large amount of C&D waste that is generated from infrastructure projects. The study is motivated by Bærum Ressursbank in Norway and their aim of finding logistical solutions to an expected surplus of 15 million m of waste from infrastructure projects in the next decade. We identify the key decisions as the design of the distribution network for both surplus waste materials and new construction materials and the investments in processing machinery at each recycling facility, and we call the problem representing this situation the Infrastructure Waste Management Problem (IWMP).

View Article and Find Full Text PDF
Article Synopsis
  • Current lung cancer treatments don't work well for everyone, and researchers want to find out why so they can make better options.
  • They discovered that changes in lung cancer cells, like mutations in certain genes (EGFR and KRAS), can produce proteins that mess with how the immune system works.
  • By reducing a protein called CCL5 in mice with lung cancer, researchers found that the immune system was able to fight the tumor better, suggesting targeting CCL5 could help improve treatments for lung cancer patients.
View Article and Find Full Text PDF