A Fully Integrated Miniaturized Optical Biosensor for Fast and Multiplexing Plasmonic Detection of High- and Low-Molecular-Weight Analytes.

Optical biosensors based on plasmonic sensing schemes combine high sensitivity and selectivity with label-free detection. However, the use of bulky optical components is still hampering the possibility of obtaining miniaturized systems required for analysis in real settings. Here, a fully miniaturized optical biosensor prototype based on plasmonic detection is demonstrated, which enables fast and multiplex sensing of analytes with high- and low molecular weight (80 000 and 582 Da) as quality and safety parameters for milk: a protein (lactoferrin) and an antibiotic (streptomycin).

ECG-Quality Assessment of Dry-Electrode Cooperative Sensors.

Classical approaches for measuring high-quality ECG require the use of gel electrodes and individually shielded cables, which limit patient comfort, especially in long-term use. We recently introduced a novel sensing architecture-so-called cooperative sensors-that allow the use of active dry electrodes connected by two unshielded wires. The aim of this work is to qualitatively evaluate an ECG recorded with a dry-electrode cooperative-sensor system.

Electromagnetic disturbances rejection with single skin contact in the context of ECG measurements with cooperative sensors.

Classical approaches to make high-quality measurements of biopotential signals require the use of shielded or multi-wire cables connecting the electrodes to a central unit in a star arrangement. Consequently, increasing the number of leads increases cabling and connector complexity which is not only limiting patient comfort but also anticipated as the main limiting factor for future miniaturization and cost reduction of tomorrow's wearables. We have recently introduced a novel sensing architecture that significantly reduces cabling complexity by eliminating shielded or multi-wire cables as well as by allowing simple connectors thanks to a bus arrangement.