Erythrophagocytosis by cultured skin fibroblasts from patients with hereditary metabolic disorders.

Phagocytosis of native allogenic red blood cells was observed in cultures of skin fibroblasts obtained from patients with neuronal ceroid-lipofuscinosis, Niemann-Pick disease type C and morbus Fabry. Occasional phagocytizing cells were observed in 9 other syndromes. Cells from three normal donors did not phagocytize.

Internalization of triiodothyronine-bovine serum albumin-colloidal gold complexes in human peripheral leukocytes.

Complexes of triiodothyronine-bovine serum albumin-colloidal gold were specifically internalized in human peripheral leukocytes after 5 min of incubation. The specificity was partially lost after a longer incubation.

Binding of (125I) triiodothyronine to human peripheral leukocytes and its internalization.

Ultrastructural autoradiography showed high specific binding of (125I) triiodothyronine, as confirmed by a competition test, to plasma membranes, nuclei and mitochondria of human peripheral leukocytes. A high level of binding was also noted on the granulocytes' granules, especially in eosinophils.

Relation between high-frequency electrical impedance and malignity of two L cell sublines.

Two L cell sublines (L-As and LC3), differing in the ability to induce sarcomas in irradiated C3H mice, were grown on special gold electrodes interrupted in the middle by a 50 micron wide slot. Electrical impedance of the two sublines was compared at 100 kHz in a special measuring device connected with an apparatus used for impedance measurement in clinics. Significantly lower values of impedance characterized the LC3 cells, which induced more sarcomas in susceptibility hosts than the L-As cells.