[Seroprevalence of human immunodeficiency virus, hepatitis B virus and hepatitis C virus among blood donors in Segou, Mali].

The purpose of this retrospective study, which examined data collected from January 2007 through September 2010, was to evaluate the seroprevalence of human immunodeficiency virus (HIV), hepatitis B virus (HBV), and hepatitis C virus (HCV) among 2946 new blood donors at the Nianankoro Fomba Hospital (NFH). The overall seroprevalence of HIV was 0.88%, of HBV 5.

[Descriptive study of diabetic foot at the Marc Sankale Diabetes Center. Report of 105 cases].

Introduction: Diabetic foot is a major complication of diabetes due to its frequency and its high risk of evolution to amputation. We report 105 cases recruited at the diabetes centre Marc Sankale.

Method: It's a prospective study including all diabetic patients who attended the diabetes centre for any foot lesion during a one year period.

[Incomplete isosexual puberty, myopathy, and pseudoprolactinoma in a 20-year-old girl with primary hypothyroidism].

Primary hypothyroidism, possibly due to Hashimoto thyroiditis in infancy, led to abnormal puberty in this girl: menstruation began at the age of 16 years, with a cycle duration of 40 days and lack of axillary and pubic hair. Hypertrophic myopathy without myotony was also present, and assays showed very low levels of follicular hormone. The severity of the primary hypothyroidism was shown by the TSH level of 236 microIU/mL, a prolactin level of 390 microU/mL and a large sella turcica.

[Medullary thyroid carcinoma and some of its particularities].

Various studies of medullary thyroid carcinoma have found its apoptosis rate to be very low. Tumor growth is usually progressive but in some cases, rapid progression and high proliferation are seen. Some mutations of the RET proto-oncogene are thought to have a direct or indirect effect on this clinical process.

[Reflections on mental retardation and congenital hypothyroidism: effects of trace mineral deficiencies].

While deficiencies of trace minerals and vitamins are rare in humans eating a variety of food, they can occur in premature infants and those with disturbances in dietary behavior for physical or psychological reasons and during parenteral or enteral nutrition. Some deficiencies - such as iron and iodine - cause such serious specific disorders that they must be considered separately. Congenital hypothyroidism induced by iodine deficiency is a major problem.