Modic type I change may predict rapid progressive, deforming disc degeneration: a prospective 1-year follow-up study.

Introduction: This prospective magnetic resonance imaging (MRI) study in chronic low-back pain (CLBP) patients evaluated the natural course of degenerative lumbar spine changes in relation to Modic 1 type changes (M1) within 1 year.

Materials And Methods: From 3,811 consecutive CLBP patients referred to lumbar spine MRI 54 patients with a large M1 were selected using strict exclusion criteria to exclude specific back disorders. Follow-up MRI was obtained within 11-18 months.

Correlation of size and type of modic types 1 and 2 lesions with clinical symptoms: a descriptive study in a subgroup of patients with chronic low back pain on the basis of a university hospital patient sample.

Study Design: Intensity of pain and level of disability (Oswestry Disability Index [ODI]) were compared with the relative size of Modic type 1 (M1) and Modic type 2 (M2) lesions. Clinical symptoms of patients having mixed M1-M2 lesion (n = 49) were compared with patients having a "pure" M1 lesion (n = 13).

Objective: To determine the relation of the sizes of M1 and M2 lesions and the type of Modic lesion (mixed M1-M2 or pure M1 lesion) with intensity of low back pain and level of perceived disability.

Relationship of Modic type 1 change with disc degeneration: a prospective MRI study.

Objective: The objective was to study the natural course of Modic type 1 change (M1) in relation to lumbar disc degeneration.

Materials And Methods: Twenty-four chronic low back pain (LBP) patients with M1 on lumbar spine were selected from 1,015 patients with magnetic resonance imaging from a follow-up study lasting for 18-74 months. Exclusion criteria were any other specific back disorder, age >or=60 years, or a recent spine operation.

MRI follow-up of subchondral signal abnormalities in a selected group of chronic low back pain patients.

Subchondral signal abnormalities have been suggested to play an important role in chronic low back pain (LBP) syndromes. Their natural course is not well known. In this study the morphology and natural course of isolated subchondral signal abnormalities in the lumbosacral spine were analyzed with MRI.

Validation study of a Finnish version of the Western Ontario and McMasters University osteoarthritis index.

The aim of the study was to validate a Finnish version of the internationally used Western Ontario and McMasters University osteoarthritis index (WOMAC) questionnaire, by testing its reliability, validity and responsiveness. The subjects of the study were patients scheduled for elective total knee arthroplasty (TKA) or total hip arthroplasty (THA). The patients completed the WOMAC questionnaire twice prior to surgery and once postoperatively to enable reliability, construct validity and responsiveness analysis.