Publications by authors named "E H Hernes"
Purpose: The introduction of immunotherapy in pleural mesothelioma (PM) has highlighted the need for effective outcome predictors. This study explores the role of [18F]FDG PET/CT in predicting outcomes in PM treated with immunotherapy.
Methods: Patients from the NIPU trial, receiving ipilimumab and nivolumab +/- telomerase vaccine in second-line, were included.
Article Synopsis
- Prostate-specific membrane antigen (PSMA) PET significantly enhances management decisions for patients with biochemically recurrent prostate cancer by revealing more positive findings compared to MRI and CT alone.
- The study analyzed data from 41 patients, showing that the combination of PET with either MRI or CT led to improved detection rates and altered treatment plans for a considerable number of patients.
- The interreader agreement improved significantly with the addition of PET, highlighting its importance in clinical assessment and decision-making.
Purpose: To evaluate the variability of the 18F-FDG-PET/CT-based metabolic tumor volume (MTV) in anal cancers during fractionated chemoradiotherapy (CRT), and assess the impact of this variability on dosimetric accuracy in MTV-targeted dose painting.
Methods: Eleven patients with anal squamous cell carcinoma who received fractionated chemoradiotherapy with curative intent were included. 18F-FDG PET/CT images were acquired at pre- and mid-treatment.
Background: Accurate target volume delineation is a prerequisite for high-precision radiotherapy. However, manual delineation is resource-demanding and prone to interobserver variation. An automatic delineation approach could potentially save time and increase delineation consistency.
View Article and Find Full Text PDFFACBC (anti-1-amino-3-F-fluorocyclobutane-1-carboxylic acid) is a FDA-approved PET-tracer in patients with suspected recurrent prostate cancer. In the diagnostic work-up of primary prostate cancer, accurate localization of the index tumor is needed for image-guidance of biopsies. We therefore assessed the performance of FACBC PET/CT to detect and localize the index tumor and compared it to multiparametric MRI (mpMRI) using whole-mount histopathology as reference standard.
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