Publications by authors named "E H A van den Munckhof"

Purpose: This study aimed to investigate the influence of bacterial vaginosis on time to pregnancy in subfertile couples.

Methods: Couples attending a teaching hospital in the Netherlands having an initial fertility assessment (IFA) between July 2019 and June 2022 were included in this prospective study, with follow-up of pregnancies until June 2023. Vaginal samples at IFA were analyzed on pH, qPCR BV, and 16S rRNA gene microbiome analysis of V1-V2 region.

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This study aimed to investigate the influence of hormonal treatment on the vaginal microbiome during fertility treatments. Bacterial vaginosis (BV) could affect fecundity, particularly in the in vitro fertilization (IVF) population, where negative effects on pregnancy outcomes have been reported. It is hypothesized that the hormone treatment during fertility treatments could influence the abundance of Lactobacilli, with negative effects on the pregnancy results.

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Background: Electroconvulsive therapy (ECT) is a highly effective treatment for major depressive episodes (MDE). However, ECT-induced cognitive side-effects remain a concern. Identification of pre-treatment predictors that contribute to these side-effects remain unclear.

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Article Synopsis
  • The study investigates the role of small intestinal bacterial overgrowth and changes in gut microbiota in patients with liver cirrhosis, linking them to bacterial translocation and potential infections.
  • Researchers analyzed duodenal samples and bacterial DNA from 103 cirrhosis patients compared to 22 non-liver disease controls, using advanced genetic sequencing techniques.
  • Results showed that cirrhosis patients had unique bacterial profiles in the duodenum, marked by higher levels of certain bacteria like Streptococcus, while overall bactDNA levels in blood and duodenal fluid were similar to controls, suggesting a specific dysbiosis associated with liver disease.
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Purpose: This study investigates the role of bacterial vaginosis (BV) on pregnancy rates during various fertility treatments. BV is known to influence several obstetric outcomes, such as preterm delivery and endometritis. Only few studies investigated the effect of BV in subfertile women, and studies found a negative effect on fecundity especially in the in vitro fertilisation population.

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