Publications by authors named "E Guillochon"

Article Synopsis
  • The study focuses on Plasmodium ovale wallikeri, a parasite that causes relapses in humans similar to Plasmodium vivax, where infections can recur after a dormant phase in the liver.
  • Researchers analyzed relapse patterns in travelers who contracted the parasite in sub-Saharan Africa and experienced these relapses after returning to France.
  • Using genetic markers, they found that most primary infections and relapses were genetically similar, providing the first genetic evidence of relapses in P ovale species.
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Since 2010, the human-infecting malaria parasite Plasmodium ovale spp. has been divided into two genetically distinct species, P. ovale wallikeri and P.

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Malaria control relies on passive case detection, and this strategy fails detecting asymptomatic infections. In addition, infections in endemic areas harbor multiple parasite genotypes that could affect case management and malaria epidemiology. Here, we performed AmpSeq genotyping to capture polymorphisms associated with antimalarial resistance and the genetic diversity within natural Plasmodium falciparum infections.

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Cerebral malaria (CM) is the severest form of Plasmodium falciparum infection. Children under 5 years old are those most vulnerable to CM, and they consequently have the highest risk of malaria-related death. Parasite-associated factors leading to CM are not yet fully elucidated.

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We retrospectively analyzed epidemiologic, clinical, and biologic characteristics of 368 Plasmodium ovale wallikeri and 309 P. ovale curtisi infections treated in France during January 2013–December 2018. P.

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