Publications by authors named "E Guevara-Sangines"
A 14-year-old male with disseminated superficial porokeratosis and a family history of the same lesions on his maternal side presented with spiny keratoderma. Spiny keratoderma is a dermatosis characterized by multiple punctate keratotic neoformations on the palms and soles. It is considered a rare disease, with fewer than 84 cases reported in the world medical literature to date.
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- The review evaluates the effectiveness and safety of Janus kinase inhibitors (JAKi) for treating moderate-to-severe atopic dermatitis (AD) in adolescents, highlighting a need for systemic therapies in this age group.
- While JAKi like abrocitinib, baricitinib, and upadacitinib show promise with quick results, baricitinib is ineffective in younger children aged 2 to 10 years.
- Major safety concerns have not emerged in adolescent trials, though there are minor issues like herpes zoster infections and acne, indicating that JAKi could be a valuable option for managing severe AD in young patients.
With the advancement of knowledge in relation to the physiopathogenesis of atopic dermatitis (AD), several new therapeutic forms have been developed. There are also new guidelines for self-care. On the other hand, there is still an underdiagnosis of AD in Mexico.
View Article and Find Full Text PDF[Assessment of quality of life illness in adult patients with atopic dermatitis].
Rev Med Inst Mex Seguro Soc
August 2021
Background: Atopic dermatitis (AD) is a disease with an impact on the patient's quality of life (QoL). Several tools have been designed to assess the clinical severity of the disease, such as the Eczema Area and Severity Index (EASI), while specific instruments have been created to assess QoL, such as the Dermatology Life Quality Index (DLQI) and the Quality of Life Index for Atopic Dermatitis (QoLIAD).
Objective: To define which tool is the best to assess the QoL condition of adult patients with AD in relation to the EASI.
Background: In Mexico, the economic burden of medical care for patients with atopic dermatitis is unknown.
Objective: To determine the annual direct medical costs of the treatment for patients with moderate to severe atopic dermatitis who receive medical attention at "Instituto de Seguridad y Servicios Sociales de los Trabajadores del Estado" (Institute for Social Security and Social Services for State Workers, better known as ISSSTE), as well as the main variables associated with it.
Methods: A multicenter, retrospective cohort study.