Publications by authors named "E Grimm"
Background: Alcohol-related hospitalizations are rising; however, medications for alcohol use disorder (M-AUD) are underprescribed despite their effectiveness to reduce heavy drinking. In-hospital administration of intramuscular (IM)-naltrexone may reduce negative health outcomes among people with AUD who are unable to take daily MAUD.
Objective: To assess addiction clinicians' perceptions of offering and administering IM-naltrexone and to assess hospitalized patients' perspectives on their alcohol use and acceptance of MAUD.
Article Synopsis
- Uveal melanoma (UM) is a serious cancer with limited treatment options, and this study investigates the effects of imipridones, which activate a protein called CLPP that can indirectly inhibit a harmful energy production process in the cancer cells.
- Researchers found that imipridones, specifically ONC201 and ONC212, reduce the growth and spread of UM cells in the lab and show promise in decreasing tumor size and increasing survival in animal models.
- The findings suggest that imipridones could be a new and effective treatment strategy for patients with metastatic uveal melanoma (mUM).
Article Synopsis
- Point-of-care lung ultrasound (LUS) is more accurate than chest X-rays for diagnosing issues causing difficulty breathing and is recommended in clinical guidelines.
- A study analyzing 820 LUS cases at a major hospital found that 90% of LUS procedures were clinically relevant, with nearly 40% leading to changes in patient management.
- The research highlights the significant role of LUS in real-world clinical settings and the need for better documentation and education in its application among medical professionals.
Purpose: We performed an exploratory evaluation of gender-specific differences in speakers and their introductions at internal medicine grand rounds.
Method: Internal medicine grand rounds video archives from three sites between December 2013 and September 2020 were manually transcribed and analyzed using natural language processing techniques. Differences in word usage by gender were compared.
Although childhood exposure to radioactive iodine-131 (I-131) is an established risk factor for thyroid cancer, evidence for an association with thyroid nodules is less clear. The objective of this study is to evaluate the association between childhood I-131 exposure and prevalence of ultrasound-detected thyroid nodules overall and by nodule histology/cytology (neoplastic/suspicious/non-neoplastic), size (<10 mm/≥10 mm), and number (single/multiple). This is a cross-sectional study of radiation dose (mean = 0.
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