Background: Enuresis, also referred to as nocturnal enuresis, is characterised by discrete episodes of urinary incontinence during sleep in children aged ≥5 years in the absence of congenital or acquired neurological disorders. This guideline is an update of the 2017 version.
Recommendations: The guideline provides recommendations and suggestions for various therapeutic options for enuresis available in South Africa (SA).
Despite the remarkable progress made in the understanding and treatment of childhood nephrotic syndrome (NS), a lot is still unknown about its epidemiology in many African countries. This study sought to determine the clinicopathological features and treatment outcomes of children with NS at the largest tertiary hospital in Botswana. A retrospective study of 26 children with NS treated from 2009 to 2014 was conducted.
View Article and Find Full Text PDFIn black African children with focal segmental glomerulosclerosis (FSGS) there are high rates of steroid resistance. The aim was to determine genetic associations with apolipoprotein L1 () renal risk variants and podocin () variants in 30 unrelated black South African children with FSGS. Three variants were genotyped and the exons of the gene sequenced in the cases and controls.
View Article and Find Full Text PDFBackground: It is important for centres participating in transplantation in South Africa (SA) to audit their outcomes. Wits Donald Gordon Medical Centre (WDGMC), Johannesburg, SA, opened a transplant unit in 2004. The first 10 years of kidney and pancreas transplantation were reviewed to determine outcomes in respect of recipient and graft survival.
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