Publications by authors named "E Gorla"
Diacylglycerol kinases (DGKs) play dual roles in cell transformation and immunosurveillance. According to cancer expression databases, acute myeloid leukemia (AML) exhibits significant overexpression of multiple DGK isoforms, including , and , without a precise correlation with specific AML subtypes. In the TGCA database, high expression negatively correlates with survival, while high expression is associated with a more favorable prognosis.
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- The study presents a high-quality genome assembly for the helmeted guinea fowl (HGF) to aid in understanding its domestication process in Africa.
- Genome analysis of 129 guinea fowl reveals domestication events occurred in West Africa approximately 1,300-5,500 years ago.
- Insights into genes related to behavior, locomotion, plumage color, and fertility were discovered, offering valuable resources for future research and breeding efforts.
Article Synopsis
- This study investigates the genomic diversity in multiple turkey populations through analysis of Copy Number Variants (CNVs) using a sample of 115 individuals from six Italian breeds, seven Narragansett, and 30 Mexican turkeys.
- Researchers utilized a 600K SNP array to genotype the birds and applied advanced software for CNV analysis, leading to the discovery of 2,987 CNVs representing 4.65% of turkey autosomes.
- The findings highlight that CNVs can effectively categorize turkeys by population and geographic origin, suggesting potential links to adaptation based on previous studies in other species.
Article Synopsis
- Copy number variants (CNVs) are key genomic variations that can affect traits in various species, but previous studies on cattle have not extensively analyzed CNV patterns using high-density SNP arrays.* ! -
- In this study, researchers conducted a high-resolution CNV scan on the Valdostana Red Pied (VRP) cattle population using a powerful Beadchip and identified 6,784 CNVs across 108 bulls, revealing distinct losses and gains in genetic information.* ! -
- Comparisons revealed that the CNVs in VRP were more similar to those in the Italian Brown Swiss breed than to the Mexican Holstein, and analyses showed three separate clusters for the breeds, highlighting genetic differentiation potentially influenced by selective breeding