Publications by authors named "E Girard"

Objectives: To identify risk factors for conversion, develop a predictive Conversion Risk Score (CRS), and assess the association between conversion and severe postoperative complications.

Background: Conversion occurs in 15-30% of minimally invasive left pancreatectomies (MILP). Risk factors and potential negative impacts on postoperative outcomes are poorly described.

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Allosteric regulation is a powerful mechanism for controlling the efficiency of enzymes. Deciphering the evolutionary mechanisms by which allosteric properties have been acquired in enzymes is of fundamental importance. We used the malate (MalDH) and lactate deydrogenases (LDHs) superfamily as model to elucidate this phenomenon.

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Article Synopsis
  • Coral reefs worldwide are suffering from coastal eutrophication, leading to decreased coral cover and increased harmful organisms like algae and invertebrates.
  • The study focuses on how micro-benthic communities, specifically foraminifera, diatoms, and bacteria, are influenced by turbidity associated with eutrophication in the Spermonde Archipelago, using environmental DNA analysis.
  • Findings indicate that shallower reef flat communities are much more affected by turbidity than deeper reef slope communities, with foraminifera and diatom ESVs serving as indicators of varying turbidity levels, thus highlighting the influence of local environmental conditions on these micro-benthic communities.
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Background: Medulloblastoma (MB) is one of the most prevalent embryonal malignant brain tumors. Current classification organizes these tumors into four molecular subgroups (WNT, SHH, Group 3, and Group 4 MB). Recently, a comprehensive classification has been established, identifying numerous subtypes, some of which exhibit a poor prognosis.

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Botulinum neurotoxin type-A (BoNT/A), which blocks quantal acetylcholine (ACh) release at the neuromuscular junction (NMJ), has demonstrated its efficacy in the symptomatic treatment of blepharospasm. In 3.89% of patients treated for blepharospasm at Tenon Hospital, BoNT/A was no longer effective in relieving the patient's symptoms, and a partial upper myectomy of the muscle was performed.

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