Urinary tract changes associated with exposure in utero to diethylstilbestrol.

Intravenous pyelograms were performed on 128 women who had been exposed in utero to diethylstilbestrol (DES). For comparison, intravenous pyelograms (IVPs) of 48 non-exposed women were reviewed: No difference in urinary tract abnormalities was noted. There was no significant increase in urinary tract abnormalities in women with upper genital tract abnormalities demonstrated by hysterosalpingogram as compared to a group of women whose x-rays of the uterus were normal.

Upper genital tract changes and pregnancy outcome in offspring exposed in utero to diethylstilbestrol.

Hysterosalpingography (HSG) was performed on 267 diethylstilbestrol (DES)-exposed women. One hundred eighty-five (69%) of these women demonstrated an abnormality and 82 women had normal findings. A relationship between abnormal x-ray findings and structural abnormalities of the cervix and vaginal epithelial changes was noted.