Publications by authors named "E Geoffrey Hancock"

Teredinibacter turnerae is a cultivable cellulolytic Gammaproteobacterium (Cellvibrionaceae) that commonly occurs as an intracellular endosymbiont in the gills of wood-eating bivalves of the family Teredinidae (shipworms). The genome of T. turnerae encodes a broad range of enzymes that deconstruct cellulose, hemicellulose and pectin and contribute to wood (lignocellulose) digestion in the shipworm gut.

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Introduction: This study explores students' and patients' views of a UK physical therapy student-led clinic (SLC) for neurological rehabilitation and, using a codesign approach, it proposes an optimal design of a physical therapy SLC for neurological rehabilitation for patient participation and student learning.

Review Of Literature: There is a paucity of literature examining experiences of neurological rehabilitation SLCs. Although research supports the utilization of codesign methodologies with patients and for curriculum development, there remains a gap regarding its application to SLCs in physical therapy for individuals with neurological conditions.

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  • Axi-cel (axi-cel) and tisagenlecleucel (tisa-cel) are advanced T-cell therapies for treating resistant diffuse large B-cell lymphoma (DLBCL), evaluated in major clinical trials (ZUMA-1 and JULIET) and a French registry that examined data from 729 patients.
  • Axi-cel showed better overall survival and progression-free survival compared to tisa-cel but was linked to more severe immune-related side effects, while no significant difference was found in serious cytokine release syndrome.
  • The cost-effectiveness analysis indicated that axi-cel is more economically favorable, costing €15,520 per quality-adjusted life year compared to tisa-cel.
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With prior knowledge of seen objects, humans have a remarkable ability to recognize novel objects using shared and distinct local attributes. This is significant for the challenging tasks of zero-shot learning (ZSL) and fine-grained visual classification (FGVC), where the discriminative attributes of objects have played an important role. Inspired by human visual attention, neural networks have widely exploited the attention mechanism to learn the locally discriminative attributes for challenging tasks.

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  • Pneumonia is frequent among adults hospitalized with confirmed influenza, but the impact of how quickly antiviral treatment is given on severe outcomes is not well understood.
  • The study analyzed data from over 26,000 adults hospitalized between 2012-2019 to see how the timing of antiviral treatment (given on the day of admission vs. later) affected 30-day mortality rates.
  • Results showed that those who received treatment later (days 2-5) had a significantly higher risk of death compared to those treated on the same day of admission, emphasizing the need for prompt treatment.
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