[Preliminary evaluation of the interest of a therapeutic optimization cell on the titration of treatments for heart failure with reduced left ventricular ejection fraction and the quality of life of patients].

Introduction: A multidisciplinary therapeutic optimization unit (COT) was created in January 2023 at Versailles Hospital, aimed at therapeutic optimisation of patients with chronic heart failure with reduced left ventricular ejection fraction. The objective of the study was to assess the impact of the first year of COT activity on the sequential implementation and titration of heart failure treatments, the clinical evolution, and improvement of patients' quality of life.

Methods: This prospective study included consecutive patients treated by the COT after hospitalisation for acute heart failure, from January to December 2023.

Design of metastable oxychalcogenide phases by topochemical (de)intercalation of sulfur in LaOS.

Designing and synthesising new metastable compounds is a major challenge of today's material science. While exploration of metastable oxides has seen decades-long advancement thanks to the topochemical deintercalation of oxygen as recently spotlighted with the discovery of nickelate superconductor, such unique synthetic pathway has not yet been found for chalcogenide compounds. Here we combine an original soft chemistry approach, structure prediction calculations and advanced electron microscopy techniques to demonstrate the topochemical deintercalation/reintercalation of sulfur in a layered oxychalcogenide leading to the design of novel metastable phases.

Toward the Coordination Fingerprint of the Edge-Sharing BO Tetrahedra.

The KSbBO (KSBO) material undergoes an uncommon symmetry increase upon cooling, from triclinic symmetry at room temperature to monoclinic symmetry at low temperature. The first-order phase transition is accompanied by shrinkage of the unit cell, resulting in the transformation of every pair of head-to-tail triangular BO groups into one BO unit featuring unique edge-sharing BO tetrahedra. This is the first material with BO units formed through temperature lowering and exhibiting a B-O anionic framework composed uniquely of isolated edge-sharing BO tetrahedra.

Layered Quaternary Compounds in the CuS-InS-GaS system.

Several new materials with four structure-types (e.g., CuInGaS (CIGS), CuInGaS (CIGS), CuInGaS (CIGS), and CuInGaS (CIGS)) have been evidenced in the CuS-InS-GaS pseudo-ternary system.

Impact of Nanostructuration on the Chemical Composition of Nickel Oxide Nanoparticles.

Reduction of the size of a particle down to a few tens of nanometers or below may drastically affect its physical properties. That is well-known for quantum dots. Conversely, many works consider the chemical composition of nanoparticles as invariant upon reduction of their dimension.