Publications by authors named "E Gatta"

: Struma ovarii (SO) is an ovarian teratoma with the presence of ectopic thyroid tissue. Differentiated thyroid cancer (DTC) in SO is a rare finding. Management of DTC in SO is currently not clearly established.

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Purposes: Evaluate the changes in quality of life (QoL) in patients affected by tertiary hyperparathyroidism (THPT) after surgical treatment using the Parathyroidectomy Assessment of Symptoms (PAS) and Short Form-36 (SF-36) questionnaires.

Methods: Single centre longitudinal retrospective, single-institution analysis of 34 patients with THPT and submitted to parathyroidectomy between 2015 and 2021. The PAS and SF-36 questionnaires were administered before surgery and 24 months after discharge.

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Hypothyroidism is typically treated with levothyroxine monotherapy. However, despite normalized serum thyroid-stimulating hormone levels, 5-10% of patients continue to experience persistent symptoms, raising concerns about the adequacy of thyroxine monotherapy. Combination therapy with levothyroxine and liothyronine has been proposed as an alternative, but it presents practical challenges, including dosing complexity, the short half-life of triiodothyronine, increased monitoring requirements, and potential adverse effects.

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Article Synopsis
  • Treating hypothyroidism is complicated for patients with malabsorption, often requiring higher doses of oral levothyroxine (L-T4) due to impaired absorption.
  • A case is presented of a young man with myxedema after undergoing biliopancreatic diversion surgery, showing severe hypothyroidism symptoms and requiring intravenous treatments.
  • The case highlights the importance of monitoring Thyroid Stimulating Hormone (TSH) levels more frequently in post-bariatric surgery patients and suggests that liquid forms of L-T4 may be more effective than tablets in these cases.
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The Antisecretory Factor (AF) is a protein that can reduce intestinal hypersecretion and various inflammation disorders . Discovered in many mammalian tissues and plasma, its mechanism of action remains unknown. Interestingly, its induction has been found to counteract vertigo in patients with Méniere's disease.

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