Publications by authors named "E Garrido"
Background: People with Multiple Sclerosis (MS) have a 20-fold higher risk of developing trigeminal neuralgia compared to the general population. Treating trigeminal neuralgia in these patients is particularly challenging due to reduced tolerance and increased side effects from medications. When no neurovascular conflict exist, percutaneous treatments are usually the first option after drug therapy.
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- The IA polymorphism is linked to both the Ankyrin Repeat and Kinase Domain-containing I gene (ANKK1) and the D2 dopamine receptor gene, posing challenges in understanding its role in addictions and psychiatric disorders due to unclear ANKK1 functions.
- Research using SH-SY5Y neuroblastoma models shows that ANKK1 interacts with FARP1, a synapse protein, contributing to neuronal maturation and the activation of the Wnt/PCP pathway while promoting neuritogenesis.
- Interactions between ANKK1 and WGEF are crucial for regulating RhoGTPases during neuronal differentiation, indicating that ANKK1 may play a significant role in organizing the brain's structural response related to IA-associated
Background: Diabetes mellitus (DM) has been associated with salivary disorders such as xerostomia and hyposalivation. The aim of this study was to determine the prevalence of these disorders and their risk factors in DM patients.
Methods: DM patients from two health centers were included.
The excessive use of biocides has considerable environmental and economic impacts; this is why new technologies have been sought to decrease the concentration levels applied in an effort to reduce the use of these substances. Microencapsulation using cyclodextrins has been widely used in the food and pharmaceutical industries as a way of reducing the concentrations of the active substance necessary to achieve a biological effect and/or eliminate its irritating or toxicological effects. In this study, the inclusion complexation behavior and binding ability of benzothiazolinone (BIT) with different β-cyclodextrins (β-CD, HP-β-CD, and Me-β-CD) was investigated.
View Article and Find Full Text PDFBackground & Aims: Fontan-type surgery is a palliative procedure for congenital heart disease with univentricular physiology that may, in the long term, lead to advanced chronic liver disease. Herein, we assessed the accuracy of conventional non-invasive models for assessing liver fibrosis in the context of Fontan circulation and developed a new risk score employing non-invasive tools.
Methods: A prospective, cross-sectional, observational study was conducted across five European centers and encompassing all consecutive adult patients with Fontan circulation, liver biopsy and non-invasive tests (e.