Publications by authors named "E Garofalo"
Introduction: High-frequency percussive ventilation (HFPV) is a ventilation mode characterised by high-frequency breaths. This study investigated the impact of HFPV on gas exchange and clinical outcomes in acute respiratory failure (ARF) patients during spontaneous breathing, noninvasive ventilation (NIV) and invasive mechanical ventilation (iMV).
Methods: This systematic review included randomised and nonrandomised studies up to August 2023.
Tracheostomy is an essential procedure in cases of respiratory failure in patients requiring long-term ventilation or showing airway obstruction. Tracheostomy has both immediate and long-term complications. Among these, tracheo-innominate fistula is an emergency that is a rare long-term complication.
View Article and Find Full Text PDFInhaled antibiotics for treating pneumonia in invasively ventilated patients in intensive care unit: a meta-analysis of randomized clinical trials with trial sequential analysis.
Crit Care
November 2024
Background: The use of inhaled antibiotics for treating pneumonia in invasively ventilated patients offers a direct approach, allowing for high local concentrations of the drug in the lower respiratory tract while simultaneously reducing systemic toxicity. However, the real efficacy and safety of nebulized antibiotics remain unclear. The aim of the present is to assess among critically adult patients with pneumonia and invasive ventilation, whether receiving adjuvant inhaled antibiotics improves the rate of microbiological eradication.
View Article and Find Full Text PDFAccuracy of preoperative lung ultrasound score for the prediction of major adverse cardiac events in elderly patients undergoing HIP surgery under spinal anesthesia: The LUSHIP multicenter observational prospective study.
Anaesth Crit Care Pain Med
December 2024
Article Synopsis
- Researchers believe that lung ultrasound scores (LUS) can better predict cardiac risks in elderly patients undergoing hip fracture surgery, compared to existing methods like the Revised Cardiac Risk Index and ASA Physical Status.
- The study involved 877 patients across 11 Italian hospitals, finding a significant correlation between higher LUS scores and complications, with a notable incidence of major adverse cardiovascular events (MACE).
- Results showed that a preoperative LUS score of 8 or higher was more effective at predicting MACE than traditional scoring methods, indicating its potential as a valuable tool for risk assessment in this patient population.
Adrenomedullin (ADM) is a vasodilatory peptide that plays a crucial role in maintaining cardiovascular health through its various biological functions. ADM was discovered in the acidic extract of human pheochromocytoma tissue and has been recognized for its significant effects on the vascular system. The main functions of ADM include vasodilation, controlling blood pressure and maintaining vascular integrity, although its role on cardiovascular health is broader.
View Article and Find Full Text PDF