Publications by authors named "E Garcia-Nieto"

Exposure to pesticides such as paraquat and 2,4-dichlorophenoxyacetic acid (2,4-D) has been linked to harmful health effects, including alterations in male reproduction. Both herbicides are widely used in developing countries and have been associated with reproductive alterations, such as disruption of spermatogenesis and steroidogenesis. The thyroid axis and Ca-permeable ion channels play a key role in these processes, and their disruption can lead to reproductive issues and even infertility.

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Article Synopsis
  • The study investigates the link between metabolic dysfunction-associated steatotic liver disease (MASLD) and immune-mediated inflammatory diseases (IMIDs), finding a higher prevalence of advanced liver disease in IMID patients compared to a matched control group.
  • Utilizing a case-control design, the research analyzed liver biopsy data and RNA sequencing from patients to identify significant differences in gene expression related to liver disease between IMID and control groups.
  • Results indicate that IMIDs not only increase the risk of advanced steatotic liver disease but also suggest a unique pathway for MASLD development in these patients, separate from traditional metabolic factors.
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A wide variety of biological functions, including those involved in the morphogenesis process of basidiomycete fungi, have been attributed to laccase enzymes. In this work, RNA interference (RNAi) was used to evaluate the role of the laccase () gene of PoB. Previously, transformant strains of were obtained and according to their level of silencing they were classified as light (T7), medium (T21) or severe (T26 and T27).

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Laccases are valuable enzymes as an excellent ecological alternative for bioremediation issues because they can oxidize persistent xenobiotic compounds. The production and characterization of extracellular laccases from saprotrophic fungi from disturbed environments have been scarcely explored, even though this could diversify their functional characteristics and expand the conditions in which they carry out their catalysis. , isolated from a disturbed forest, produces an extracellular laccase in liquid culture.

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Reproductive biology is an important topic that is well explored in many vertebrates, but information about frogs' reproductive mechanisms could be improved. Therefore, this review aims to provide organized and specific information on frog reproduction. First, we developed schemes that illustrate the general information regarding reproductive biological mechanisms in frogs in a specific way.

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