Publications by authors named "E Garcia-Lagarto"
Focal reactive nodular gliosis (FRNG) is an extremely rare benign retinal reactive astrocytic tumor that results from the proliferation of well-differentiated glial cells secondary to a variety of retinal conditions. We describe a case of this tumor in a 64-year-old male in association with a chorioretinal scar he has had since childhood. The symptom was sudden painful vision loss.
View Article and Find Full Text PDFClinic-pathological agreement in the diagnosis of conjunctival tumours: Analysis of 195 cases.
Arch Soc Esp Oftalmol (Engl Ed)
August 2023
Purpose: The present study aims to assess the agreement between clinical and pathological diagnosis in conjunctival tumours in a specialist ocular oncology unit.
Methods: retrospective study of consecutive patients with conjunctival tumours diagnosed at the Ocular Oncology Unit of the University Hospital of Valladolid was performed from 1992 to 2017. Tumours were classified according to their origin (epithelial, melanocytic, lymphoid and others) and degree of malignancy (benign, premalignant, malignant).
Article Synopsis
- Solitary fibrous tumors (SFTs) are neoplasms originating from fusiform mesenchymal cells, primarily found in the meninges of the central nervous system, and while often benign, they can exhibit malignant behaviors in recurrences or metastases.
- Recent research has identified the NAB2-STAT6 gene fusion as a key molecular characteristic of SFTs, which is linked to the overexpression of the NAB2-STAT6 protein in tumor cells.
- The article highlights the importance of differentiating SFTs from hemangiopericytomas (HPC) due to distinct features that affect diagnosis, treatment, and prognosis.
Purpose: Conjunctival melanoma is a rare and aggressive tumor with a propensity for regional and distant metastases. This study aimed to analyze BRAF/NRAS markers in conjunctival melanoma and their relationship with tumor recurrences and patient prognosis.
Methods: This retrospective, observational, single-center study included consecutive patients with an anatomopathological diagnosis of conjunctival melanoma, registered between January 1992 and December 2019.
A 68 year-old male was referred for assessment of an amelanotic lesion in the right eye (RE) that was associated with a gradual loss of visual acuity (VA), of 2 months onset, as the main symptom. It was noted in his medical history, that 6 years ago, he had prostate cancer treated with prostatectomy, lymphadenectomy, and coadjuvant local radiotherapy (RT). He was asymptomatic until 6 months ago, when a metastasis was discovered in the left femur, which was treated with radiotherapy.
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