Publications by authors named "E Garabedian"
Objective: The objective was to assess Potsic, EAONO/JOS, STAMCO, and ChOLE cholesteatoma staging systems in a large homogenous pediatric cohort with long-term follow-up and propose an evidence-based improved version.
Study Design: Cohort study.
Setting: Retrospective study in a tertiary referral center.
Article Synopsis
- The CDC and ACIP endorse COVID-19 vaccination for patients with inborn errors of immunity (IEI), but there's limited knowledge on its safety and impact on infection severity in these patients.
- A study involving a registry of 1,245 IEI patients across 24 countries was conducted to gather data on vaccination frequency, safety, and effectiveness, revealing that 64.7% were vaccinated, primarily with mRNA vaccines.
- Results showed that vaccinated patients had significantly lower hospitalization and ICU admission rates when infected with COVID-19, indicating that vaccination is both safe and effective in reducing the severity of the disease in IEI patients.
Purpose: There are currently more than 480 primary immune deficiency (PID) diseases and about 7000 rare diseases that together afflict around 1 in every 17 humans. Computational aids based on data mining and machine learning might facilitate the diagnostic task by extracting rules from large datasets and making predictions when faced with new problem cases. In a proof-of-concept data mining study, we aimed to predict PID diagnoses using a supervised machine learning algorithm based on classification tree boosting.
View Article and Find Full Text PDFWhat defines a great surgeon? A survey study confronting perspectives.
Front Med (Lausanne)
June 2023
Article Synopsis
- The study aimed to create a comprehensive definition of a surgeon by gathering perspectives from patients, healthcare workers, and surgeons.
- An online questionnaire collected respondents' views on essential qualities and shortcomings of surgeons, analyzing responses based on themes like human qualities, technical skills, and knowledge.
- Key findings showed dexterity as the top quality, but emphasized that human traits, especially empathy, are crucial; also, surgeons valued knowledge more than non-surgeons did, indicating a need for better recognition of this aspect.
Performance of Non-EPI DW MRI for Pediatric Cholesteatoma Follow-Up.
Otolaryngol Head Neck Surg
January 2024
Objective: To evaluate the accuracy, sensitivity, and specificity of nonecho planar (non-EPI) diffusion-weighted (DW) magnetic resonance imaging (MRI) to detect residual cholesteatoma in children.
Study Design: Retrospective study.
Setting: Tertiary comprehensive hospital.