We affirm the utility of integrative modeling, according to which it is advantageous to move beyond "one-at-a-time binary paradigms" through studies that position themselves within realistic multidimensional design spaces. We extend the integrative modeling approach to a target domain with which we are familiar, the consequences of bilingualism on mind and brain, often referred to as the "bilingual advantage." In doing so, we highlight work from our group consistent with integrative modeling.
View Article and Find Full Text PDFThe objective of this research is to demonstrate how similarity metrics can be used to quantify differences between sets of diffraction patterns. A set of 49 similarity metrics is implemented to analyze and quantify similarities between different Gaussian-based peak responses, as a surrogate for different characteristics in X-ray diffraction (XRD) patterns. A methodological approach was used to identify and demonstrate how sensitive these metrics are to expected peak features.
View Article and Find Full Text PDFSome natural and synthetic protease inhibitors (PI), such as the Bowman-Birk PI from soybean, have anticancer effects. We previously purified and characterized a Bowman-Birk-type PI from Tepary bean (Phaseolus acutifolius) seeds (TBPI). A semipure protein fraction containing this inhibitor, when tested its in vitro effect on transformed cells, showed a differential cytotoxic effect, as well as an increase in cell attachment to culture dishes.
View Article and Find Full Text PDFBackground: Ocular lymphomas and ocular adnexae lymphomas (OL and OAL) constitute 7-8% of all extranodal lymphomas.
Objective: Describe the clinical, morphologic and immunophenotypic characteristics of OAL seen in our hospital.
Material And Methods: Retrospective analysis of patient records with OL and OAL between July 1994 and July 2005.