Publications by authors named "E G Zotkin"
[Clinical and laboratory features of rheumatoid arthritis in men depending on testosterone levels].
Probl Endokrinol (Mosk)
November 2023
Background: It has been suggested that the presence of chronic immunoinflammatory rheumatic disease (CIRD) may be a factor that increases the likelihood of developing hypogonadism syndrome, and conversely, the presence of uncompensated testosterone deficiency may predispose to a greater risk of developing or more severe course of ICRD.
Aim: To study the incidence of hypogonadism in men with rheumatoid arthritis (RA) and evaluate its impact on the course of RA and concomitant diseases.
Materials And Methods: A one-time continuous study included 170 men with RA who were undergoing inpatient treatment at the Federal State Budgetary Institution NIIR named after.
Article Synopsis
- The study aimed to examine the prevalence of hypogonadism (HG) in men with rheumatoid arthritis (RA), ankylosing spondylitis (AS), and psoriatic arthritis (PsA) while also assessing its effects on these conditions.
- It involved 312 male participants who were evaluated for testosterone levels and compared across various clinical measures related to their rheumatic diseases.
- Results indicated varying rates of testosterone deficiency—24.1% in RA, 17.5% in AS, and 31.8% in PsA—with HG linked to higher body mass index and metabolic indicators, but without significant differences in testosterone and hormone levels across the rheumatic disease groups.
Article Synopsis
- - Autoimmune polyglandular syndromes (APS) are conditions where multiple endocrine glands are impaired due to immune system issues, potentially affecting other non-endocrine organs as well.
- - APS is categorized into two main types: the rare juvenile type (APS 1), which results from a single genetic mutation, and the more common adult types (APS 2-4) that have a complex genetic basis.
- - One adult subtype, APS 3D, links autoimmune thyroid disease with autoimmune rheumatic disease, showing a notable increase in rheumatic diseases among patients with thyroid conditions as compared to healthy individuals.
[Impact of surgical treatment of morbid obesity on joint diseases].
Probl Endokrinol (Mosk)
August 2023
The prevalence of obesity in the modern world is increasing. Obesity is an independent risk factor for some rheumatic diseases and also worsens their course. The presence of chronic joint disease can make it difficult for obesity to reduce activity, creating a vicious circle where joint pain makes exercise difficult and being overweight exacerbates joint pain.
View Article and Find Full Text PDFSexual dimorphism of chronic diseases is a phenomenon determined by differences in the hormonal status of men and women. In this regard, estrogens, which have a complex effect on the body, are of great interest. In particular, estrogens play an important role in the natural control of pain and inflammation.
View Article and Find Full Text PDF