Publications by authors named "E G Stenger"
Article Synopsis
- * A retrospective study analyzed data from 5,790 young patients who underwent HCT to evaluate the incidence of late effects and their associated risk factors, focusing on various health complications like avascular necrosis and diabetes.
- * The study included patients from diverse backgrounds, revealing that 60.5% were male and most were white, with major findings regarding the timing and prevalence of complications occurring within five to seven years post-transplant.
We prospectively collected PROMIS©25 and PROMIS©29 surveys in the Sickle Cell Transplant Evaluation of Long Term and Late Effects Registry (STELLAR). Mobility and social participation T-scores were decreased; all other domains were within the norm.
View Article and Find Full Text PDFConditioning regimens for hematopoietic cell transplant (HCT) in patients with sickle cell disease (SCD) place patients at risk for reproductive health issues. The purpose of this study was to assess reproductive health and reports of fertility counseling in patients with SCD who received a transplant. This was a secondary analysis of gonadal hormone production, future infertility risk assessment, and parent-proxy/patient reports of fertility counseling in SCD transplant recipients who are currently pubertal and were enrolled in the Atlanta sites of the Sickle Cell Transplant Evaluation of Long-term and Late Effects Registry (STELLAR) between May 2017 and October 2023.
View Article and Find Full Text PDFConsensus diagnostic and risk stratification of transplantation-associated thrombotic microangiopathy (TA-TMA) was recently achieved from international transplantation groups. Although the proposed diagnostic criteria have been applied to multiple pediatric cohorts, there are scant data applying the novel risk stratification approach in children with TA-TMA. In this retrospective cohort study, all children undergoing an allogeneic HCT or autologous HCT for neuroblastoma were prospectively screened for TA-TMA, diagnosed, and risk-stratified using the Jodele criteria from August 2019 to October 2023.
View Article and Find Full Text PDFArticle Synopsis
- Most data on transplant-associated thrombotic microangiopathy (TA-TMA) risk factors comes from children and young adults, with limited information on age variations in risk and outcomes.
- In an analysis of patients who underwent allogenic hematopoietic cell transplantation from 2008 to 2016, the incidence of TA-TMA was found to be similar in both children (2.1%) and adults (2.0%).
- Key risk factors for developing TA-TMA included acute graft-versus-host disease, with additional risks in adults related to female sex and black race, while children's risks included having an unrelated donor; timing of TA-TMA diagnosis was also a new risk factor for death.