Mortality in Parkinson's disease and its association with dementia and depression.

Objective: To compare the mortality rate in Parkinson's disease (PD) with a control group without PD, and to assess the relationship between mortality and features of PD.

Material And Methods: Ninety PD patients and 50 controls, mortality ascertained at 11 years follow-up.

Results: The hazard ratio (HR) for mortality in PD patients compared with controls was 1.

A 10-year study of the incidence of and factors predicting dementia in Parkinson's disease.

Objective: To compare the incidence of dementia in PD with that of a control group without PD, and to assess the relationship between dementia and other features of PD.

Methods: The authors recruited 83 patients with PD and 50 controls, all without dementia at initial assessment, and assessed them at regular intervals over a maximum period of 122 months. Dementia was diagnosed according to objective criteria, and included a judgment by researchers masked to subject group and to variables putatively associated with dementia.