[Histochemical and biochemical study of radiation injury of the kidneys in gas hypoxia].

A radioprotective effect of hypoxia was studied in kidney radiation. The use of hypoxic respiratory mixture containing 8% oxygen (the normal content is 21%) enhances kidney resistance to local single and fractionated irradiation. Determination of renal activity of succinate dehydrogenase, lactate dehydrogenase, acid and alkaline phosphatase and urinary N-acetyl-beta-D-glucosaminidase, gamma-glutamyl transferase, alkaline phosphatase, lactate dehydrogenase is recommended as tests for kidney radiation damage.

[Morphofunctional characteristics of murine kidneys in single and fractionated irradiation in air and hypoxia (8% of O2)].

The protective effect of hypoxic gas mixture containing 8% of oxygen (HGM-8) has been studied in long terms after local single and fractional X-ray irradiation of the kidney in mice. Some criteria of injury shown that hypoxia protects the kidneys against irradiation, changes in irradiation dose constituting 1.25-1.

[Disordered lipid peroxidation and ATPase activities in patients with disseminated sclerosis].

Changes of ATP-ase activity and accumulation of lipid peroxidation products in patients with multiple sclerosis depended on the clinical course of the disease. Exacerbation is accompanied by an increased activity of Mg2(+)-dependent ATP-ase and reduction of Ca2(+)-dependent ATP-ase in the leucocytes. These changes were not revealed during remission.

[Folic acid in the combined treatment of patients with disseminated sclerosis and chronic gastritis].

Folic acid was used for the complex treatment of patients with multiple sclerosis. The doses employed were 200-300 mcg daily. It was established that folic acid improved the reparative processes in the gastric mucosa and produced a pronounced therapeutic effect on the neurological status of the patients, favoured improvement of their general condition.