[Inhibitors of the nitrite oxidation of hemoglobin].

Different types of active inhibitors of the reaction of nitrite hemoglobin oxidation have been revealed and studied. The dependence of inhibition of methemoglobin formation, on concentration of inhibitors at pH 5.9 and 7.

[Effect of cycloheximide and actinomycin D on the phospholipid and neutral lipid content of Cunninghamella japonica].

Changes in the composition of neutral lipids and phospholipids were studied during the growth of Cunninghamella japonica under the action of cycloheximide and actinomycin D. The data were used to discuss how the synthesis of enzymes catalysing the formation of individual lipid classes was regulated and whether it would be possible to control the composition of phospholipids and neutral lipids using inhibitors of RNA and protein synthesis. The results are also indicative of a certain correlation between growth phases of the fungus and changes in certain characteristics of membrane lipids.

[Inhibitors of nitrite oxidation of hemoglobin].

The effects of sodium benzoate, ascorbic acid and cystein on the kinetics of oxidation of oxyhemoglobin in the presence of sodium nitrite were studied. It was shown that sodium benzoate and ascorbic acid suppress nitrite methemoglobin formation more intensively than cystein. Both compounds can also inhibit nitrite oxidation of intraerythrocyte hemoglobin.