[NO-dependent mechanisms of cardioprotective activity of MT preparation during course administration to SHR rats].

Chronic (15 days) single daily intraperitoneal insertion of the new preparation MT (5 mg/kg) and metoprolol (10 mg/kg) into SHR rats leads to the same decrease (18%) in arterial pressure. In addition, MT exhibits a cardioprotective effect because of NO-mimetic properties, increasing NO formation in myocardium via increasing general NOS activity and eNOS expression. MT normalizes iNOS expression in myocardium mitochondria and decreases nitrotyrosine (nitrosation stress marker) formation.

[The results of work and experience of the Central Research Institute of Tuberculosis, Russian Academy of Medical Sciences, in the pilot areas in controlling, detecting, and treating tuberculosis (a cohort analysis)].

In the Russian Federation, the WHO program was launched in 1994 and it covered the whole country by 2005. Detection and therapeutic efficiency are suboptimal. The proportion of pulmonary tuberculosis averages 34.

[Day-care clinics in mass screening of the population].

Day hospital at the out-patient department may be well included into the organizational and technological links of the dispensarization of population. The effective introduction of a day hospital into the dispensarization system does not take place automatically but require the complex of administrative pressures, regulation and purposeful completion of which is ensured by the use of organizational projecting technique.