Publications by authors named "E G Bakulina"
Objective: The study aimed to evaluate the epidemiological, clinical, and molecular data of mucopolysaccharidosis type II (MPS II) patients and their outcomes using the national registry of patients in the Russian Federation (RF). Materials and Methods: In the retrospective cohort study, the authors included data from the Russian national registry of MPS II. Results: The prevalence of MPS II in RF is 0.
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- The study aimed to identify why patients with chronic heart failure (CHF) in Russia have a poor prognosis, using data from various population samples and medical records over several years.
- It established the prevalence of CHF in the Russian population, finding that 8.2% of individuals meet soft criteria for CHF, while 3.1% met strict criteria, with significant influences from conditions like hypertension and ischemic heart disease.
- The prognosis for these patients is grim, with over half dying within four years after acute decompensated heart failure (ADHF), and most patients with severe CHF not surviving beyond ten years, primarily due to inadequate medication use and poor patient follow-up.
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- The study aimed to determine the prevalence of atrial fibrillation (AF) in a sample from the European part of Russia and assess patient characteristics, including anticoagulant treatment frequency.
- The findings revealed that AF prevalence was 2.04%, significantly higher in older individuals, especially those over 80, and was more common in women compared to men; individuals with multiple health conditions also showed increased AF rates.
- Despite a high need for treatment, only 22.6% of patients with AF and concomitant cardiovascular diseases were on anticoagulants, highlighting a gap in necessary care for this condition.
Article Synopsis
- This study investigated the causes and trends in the prevalence and mortality rates of chronic heart failure (CHF) in the European part of the Russian Federation over a 20-year period, focusing on treatment coverage and patient outcomes.
- The research revealed a decrease in major CHF symptoms but an increase in the overall prevalence of cardiovascular diseases, with the prevalence of CHF functional classes rising from 6.1% to 8.2%.
- Key causes of CHF were identified as arterial hypertension and ischemic heart disease, and while treatment options improved, the prognosis remained poor, with median survival times of 8.4 years for less severe cases and 3.8 years for more severe cases.
Cerebral toxoplasmosis is a leading cause of the central nervous system disorders in acquired immune deficiency syndrome. This study aimed to investigate the clinical course of cerebral toxoplasmosis in human immunodeficiency virus (HIV)-infected individuals. The study included 90 HIV-infected patients with cerebral toxoplasmosis, who underwent inpatient treatment.
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