Three modes of interactions between anions and phenolic macrocycles: a comparative study.

Macrocyclic polyphenolic compounds such as resorcin[4]arenes can be considered as multidentate anion receptors. In the current work, we combine new experimental data and reports from the previous literature (solution data and deposited crystal structures from the CCDC) to systematically analyze binding motifs between resorcin[4]arene derivatives and anions, determine the role of supporting interactions from CH donors, ion pairing and estimate their relative strength. We have found that in medium polarity solvents (THF) anion binding is a main driving force for the formation of complexes between resorcinarenes and AlkNX salts.

[Pantogam active in the complex treatment of dystonic hyperkineses].

Efficacy of pantogam active in the complex treatment of facial and cervical dystonic hyperkineses was studied in 37 patients (25 women, 12 men) with dystonic torticollis, blepharospasm, oromandibular dystonia with illness duration more than 6 months. In these patients, the previous treatment had no positive effect. Pantogam active was prescribed in dose 900-1800 mg/day during 12 weeks.

[The demonstration of specific Salmonella typhi antigens by the latex agglutination method].

The evaluation of the diagnostic importance of the method of latex agglutination with antibody diagnostica for the detection S.typhi O and Vi antigens in biosubstrates obtained from patients is presented. The clinical approbation of the method has made it possible to characterize its diagnostic specificity (whose indices varied from 95.