[The psychological characteristics of interaction between patient and physician of traumatology department].

The actual conditions of "physician-patient" interaction in hospital department presents high requirements to quality and rate of provided services. The development of conflicts because of misunderstanding of behavior motivation of physician and patient in hospital department determined purpose of actual study. The standardized psychological questionnaire "Big Five" and Myers-Briggs questionnaire were used to obtain needed data.

[The relationship between the fate of the agent of toxoplasmosis, Toxoplasma gondii, in macrophages cultivated in vitro and the virulence of the parasites].

Comparative light microscopic and electron microscopic studies of development of a highly-virulent RH strain and a less virulent Lagrave strain of Toxoplasma cultivated in macrophages in vitro were made. Contrary to active multiplication of the highly virulent strain most of toxoplasmas of a less virulent strain disintegrated the first hours, degenerating completely in 24-48 hours after the penetration into the macrophages. Submicroscopic study showed no marked cytological changes of macrophages infected with a less virulent strain in comparison with the marked changes of the nuclei in macrophages infected with the RH strain.

Interaction between macrophages of various origin and Toxoplasma gondii under conditions in vitro.

The study of proliferation of a virulent strain of Toxoplasma in cultures of macrophages of various origin revealed a certain sequence in the development of the pathogen: penetration and phagocytosis of the parasite, the stage of disintegration of one part of population and active proliferation of the other, resulting in the destruction of host cells. It was found that the penetration and phacocytosis were more active if macrophages from resistant animals (rats) were used, in comparison with those isolated from susceptible animals (white mice, guinea pigs). The activity of proliferation of a virulent strain of Toxoplasma also differs with the host cells: the toxoplasma multiply more rapidly in macrophages from susceptible animals than in those from resistant animals.