Publications by authors named "E Fredericks"

Article Synopsis
  • This study focuses on the use of noninvasive diagnostic methods to detect esophageal varices (EVs) in patients with compensated cirrhosis, contrasting with the traditional invasive method of upper endoscopy.
  • Conducted on 50 patients at a hospital in Cape Town, the study analyzed various clinical and lab data, showing that 68% of participants had EVs, primarily caused by alcohol, hepatitis B, or autoimmune factors.
  • Key findings emphasize significant differences in factors like liver and spleen stiffness, platelet counts, and dimensions that could enhance the accuracy of noninvasive tools for identifying EVs in patients.
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Background: Solid organ transplantation (SOT) offers improved long-term survival for youth with end-stage organ disease. From a neurodevelopmental, cognitive, and academic perspective, children with solid organ transplant have a number of unique risk factors. While cognitive functioning may improve post-transplantation, it is important to understand the trajectory of neurocognitive development starting in transplant candidacy to evaluate the implications of early deficits.

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Article Synopsis
  • - Over 30% of the global population is affected by anaemia, particularly iron deficiency anaemia, which is often linked to gastrointestinal issues; thus, a referral to a gastroenterologist is crucial for diagnosis.
  • - In sub-Saharan Africa, new guidelines aim to improve management of patients with iron deficiency by focusing on the evaluation of gastrointestinal causes, enhancing clinical outcomes, and ensuring efficient use of blood resources.
  • - The guidance document was created through collaboration among 21 experts in gastroenterology and haematology, using a structured process that included literature reviews, drafting recommendations, and multiple rounds of consensus voting.
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Background: The process of transition to adult-based care encompasses a critical period in the life of an adolescent and young adult living with a chronic illness and one that comes with an increase in the risk of poor health outcomes. As yet, there is a dearth of empirical data to help optimize this process to ensure the best long-term outcome.

Methods: This study used a principal components analysis to determine specific constructs measured by a revised version of the transition readiness survey used in our clinic.

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Importance: Despite high disease morbidity and mortality and complex treatment decisions, little is known about the medical and end-of-life decision-making preferences of adolescents and young adults (AYA) with advanced heart disease. AYA decision-making involvement is associated with important outcomes in other chronic illness groups.

Objective: To characterize decision-making preferences of AYAs with advanced heart disease and their parents and determine factors associated with these preferences.

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