Publications by authors named "E Fiona Leitch"

Background: Burn mass casualty incidents can overwhelm local resources, challenging effective communication, triage, and provision of care. International responders can help by providing education and direct patient care.

Local Problem: On November 5, 2021, a fuel tanker truck exploded in Freetown, Sierra Leone, killing or injuring hundreds of people.

View Article and Find Full Text PDF

Objective analysis of rotator cuff (RC) atrophy and fatty infiltration (FI) from clinical MRI is limited by qualitative measures and variation in scapular coverage. The goals of this study were to: develop/evaluate a method to quantify RC muscle size, atrophy, and FI from clinical MRIs (with typical lateral only coverage) and then quantify the effects of age and sex on RC muscle. To develop the method, 47 full scapula coverage CTs with matching clinical MRIs were used to: correct for variation in scan capture, and ensure impactful information of the RC is measured.

View Article and Find Full Text PDF

The authors aimed to develop and validate an automated artificial intelligence (AI) algorithm for three-dimensional (3D) segmentation of all four rotator cuff (RC) muscles to quantify intramuscular fat infiltration (FI) and individual muscle volume. The dataset included retrospectively collected RC MRI scans in 232 patients (63 with normal RCs, 169 with RC tears). A two-stage AI model was developed to segment all RC muscles and their FI in each stage.

View Article and Find Full Text PDF
Article Synopsis
  • Hepatitis C virus (HCV) shows high genetic diversity, particularly among strains found in the Li ethnic group on Hainan Island, China, where new strains of HCV genotype 6 (gt6) were identified.
  • Researchers sequenced 33 complete HCV genomes and found three new clades and 30 unassigned strains of gt6, showing a long history of HCV presence, dating back to roughly 2767 BCE.
  • The study indicates that the HCV gt6 strains were likely introduced to the Li community through multiple independent transmission events, shedding light on the evolutionary history of this virus.
View Article and Find Full Text PDF

Aim: Some patients with intestinal failure requiring home parenteral support (HPS) may be weaned. This study considered all abdominal surgery in a cohort of HPS patients over a 25-year period. Our aim was to identify how many patients can be weaned from HPS and by what means, and to identify what makes weaning more likely.

View Article and Find Full Text PDF