Brain metastases: Single-dose radiosurgery versus hypofractionated stereotactic radiotherapy: A retrospective study.

Background: Radiosurgery is employed for the treatment of brain metastases. The aim of this study is to evaluate the efficacy and tolerability of single-dose radiosurgery (SRS) compared to hypofractionated stereotactic radiotherapy (hFSRT).

Materials And Methods: Between 2004 and 2018, we analyzed treatments of 97 patients with 135 brain metastases.

Radiotherapy for isolated granulocytic sarcoma: Case report and review of literature.

•Isolated chloroma should be considered as a systemic disease.•Consolidation radiotherapy has been related with prolonged failure free survival.•Excellent local control of chloroma is achieved with low-dose radiotherapy.

Treatment of symptomatic splenomegaly with low doses of radiotherapy: Retrospective analysis and review of the literature.

Objectives: To evaluate the effectiveness of low doses of radiation therapy for symptomatic splenomegaly in malignant and benign diseases.

Patients And Methods: 5 patients with symptomatic splenomegaly were treated with low doses of radiation in our centre (January 2008-December 2016). 4/5 patients had malignant neoplasia (acute myeloid leukemia, non Hogdkin lymphoma and prolymphocytic B cell leukemia) and splenomegaly was caused by extramedullary hematopoiesis.

Colorectal Cancer: From the Genetic Model to Posttranscriptional Regulation by Noncoding RNAs.

Colorectal cancer is the third most common form of cancer in developed countries and, despite the improvements achieved in its treatment options, remains as one of the main causes of cancer-related death. In this review, we first focus on colorectal carcinogenesis and on the genetic and epigenetic alterations involved. In addition, noncoding RNAs have been shown to be important regulators of gene expression.

Pilot study of feasibility and dosimetric comparison of prone versus supine breast radiotherapy.

Purpose: The aim of this study was to demonstrate feasibility and analyze dosimetric differences in prone and supine position breast cancer radiotherapy in women with large or pendulous breast.

Methods: Ten post-lumpectomy breast cancer patients underwent supine and prone computed tomography-based treatment plan. On each data set, the whole breast, the ipsilateral lung and the heart were outlined.