Possibilities of metabolic endoradiotherapy with P32 in the prevention of osseous metastases from breast neoplasms. Note II.

To reach a definitive conclusion on the value of using 32P in the prophylaxis of bone metastases in association with surgical and traditional radiotherapeutic treatment, observations should be extended to a much greater number of cases. This notwithstanding, the results obtained justify this methodology based on continuous sustained, internal irradiation which would seem to make possible a diminution in the frequency of bone metastases in the early years of a delay in their onset.

[Metabolic endoradiotherapy with P32 in skeletal metastases from breast neoplasms. Note I].

22 patients suffering from breast neoplasia with particularly painful bone metastasis were treated with radiophosphorus. Only occasionally was an evident recalcification condition encountered and survival, although exceptional in some cases, did not deviate from normal. On the basis, also, of clinical and experimental observations reported in the literature, it is held that the use of 32P in metabolic radiotherapy of bone metastases is worthwhile and is justified because of the encouraging successes obtained, especially in pain remission.