Publications by authors named "E F Vanderstraeten"
This article describes the case of a 73-year-old patient with grade 3 immune checkpoint inhibitor (ICI)-induced enteritis. Five different immunosuppressive agents (glucocorticoids, high-dose infliximab, methotrexate, mycophenolate mofetil, and vedolizumab) were administered, however, with no clinical or radiographical benefit. A laparotomy was performed, as the patient showed signs of intestinal obstruction, with a segmental resection of the ileal loop.
View Article and Find Full Text PDFBackground: Gastric non-Helicobacter pylori Helicobacter (NHPH) species naturally associated with animals have been linked with gastric disease in human patients.
Aim: The prevalence and clinical significance of zoonotic gastric NHPHs was determined in large and well-defined, H. pylori-negative, gastric patient populations.
Article Synopsis
- This study examines the effects of switching patients with inflammatory bowel disease from the original adalimumab drug to its biosimilar, SB5, particularly focusing on trough levels, effectiveness, and patient satisfaction.* -
- Conducted on 110 patients, it found that after the switch, trough levels stayed in the therapeutic range, with an 84.6% acceptance rate and 74.5% drug persistence after 12 months, demonstrating good patient compliance.* -
- Results indicated no significant deterioration in disease activity and a high level of patient satisfaction, though some patients experienced injection site pain, which was generally mild and limited to the initial 30 minutes post-injection.*
Background And Study Aims: Advanced liver disease frequently culminates in hepatic encephalopathy (HE), which can be classified as covert or overt HE, with subtle or clinically obvious changes respectively. 30-40% of patients with cirrhosis develop overt HE, which negatively affects the patients' quality of life. Next to lactulose, rifaximin-α has been prescribed as a second line therapy to treat and reduce the risk of recurrence of overt HE.
View Article and Find Full Text PDFEsophageal carcinoma as a portal of entry for brainstem abscess formation.
Acta Gastroenterol Belg
March 2022
Cerebral abscess formation is a serious and life-threatening clinical entity, secondary to contiguous spread, hematogenous dissemination or direct inoculation. We present the case of a 61-year-old woman with a recent diagnosis of a locally advanced squamous cell carcinoma of the esophagus who was diagnosed with a brainstem abscess. In literature we only found three cases reporting cerebral abscess formation in patients with esophageal carcinoma.
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