Advancing Medical Education: Performance of Generative Artificial Intelligence Models on Otolaryngology Board Preparation Questions With Image Analysis Insights.

Objective  To evaluate and compare the performance of Chat Generative Pre-Trained Transformer (ChatGPT), GPT-4, and Google Bard on United States otolaryngology board-style questions to scale their ability to act as an adjunctive study tool and resource for students and doctors. Methods A 1077 text question and 60 image-based questions from the otolaryngology board exam preparation tool BoardVitals were inputted into ChatGPT, GPT-4, and Google Bard. The questions were scaled true or false, depending on whether the artificial intelligence (AI) modality provided the correct response.

Cardiac Tumors: Review.

Cardiac tumors are rare and encompass a variety of presentations. Clinica symptoms are usually nonspecific, but they can present as obstructive, embolic, or constitutional symptoms. Treatment options and prognosis vary highly depending on the subtype, tumor size, and location.

miR-497 Target Gene Regulatory Network in Angiosarcoma.

Angiosarcoma is a vascular sarcoma that is highly aggressive and metastatic. Because of its rarity, treatment options for patients are limited. Therefore, more research is needed to identify possible therapeutic vulnerabilities.

Target gene regulatory network of miR-497 in angiosarcoma.

Angiosarcoma (AS) is a vascular sarcoma that is highly aggressive and metastatic. Due to its rarity, treatment options for patients are limited, therefore more research is needed to identify possible therapeutic vulnerabilities. We previously found that conditional deletion of drives AS development in mice.

Selective targeting of Scn8a prevents seizure development in a mouse model of mesial temporal lobe epilepsy.

We previously found that genetic mutants with reduced expression or activity of Scn8a are resistant to induced seizures and that co-segregation of a mutant Scn8a allele can increase survival and seizure resistance of Scn1a mutant mice. In contrast, Scn8a expression is increased in the hippocampus following status epilepticus and amygdala kindling. These findings point to Scn8a as a promising therapeutic target for epilepsy and raise the possibility that aberrant overexpression of Scn8a in limbic structures may contribute to some epilepsies, including temporal lobe epilepsy.