[Effects of plasminogen and streptokinase on the vital functions of nervous tissue cells in culture].

In the protein-deficient media plasminogen stimulated the vital functions of cells and in concentrations 10(-7)-10(-10) M it protected cells of sympathetic ganglia, neocortex and continues cell lines under damaging actions of H2O2 (0.0001 M), NH4CI (0.01 M) and cooling.

[The role of polypeptide growth factors and hormones in the formation of neuromediator status of a sympathoadrenal cell line].

Formation of the mixed pattern of neurotransmitter synthesis at intermediate stage of neuron functional differentiation involving interaction of nerve and epidermal growth factors (NGF and EGF) and also thyroxine was analysed histochemically. Analysis of change dynamics of acetyl cholinesterase catecholamine ratio influenced by NGF demonstrated its dependence on the cell type. Thyroxine potentiates NGF effect while EGF stimulates NGF-induced ACE increase only during the initial period.