[Effect of an intervention in physical education classes on the reduction of sedentary behavior in adolescents].

This study aimed to analyze the effect of different intervention strategies in physical education classes on the reduction of sedentary time. This is a randomized, school-based intervention with factorial characteristics, carried out with freshmen high school students from 11 full-time schools, allocated in three intervention situations: (A) schools with two extra physical education classes per week; (B) schools with training and engagement actions for physical education teachers; (C) Schools with both A and B strategies; and (D) a group of control schools. Accelerometry was used to obtain the effect measure of the main outcome (sedentary behavior).

Use of Virtual Reality Glasses During Healthcare: An Integrative Review.

Integrating technology into healthcare services has direct implications for the efficacy and performance of client care. In view of this, the aim was to identify the possibilities of using virtual reality glasses in healthcare. An integrative literature review was conducted in October 2024, searching in MEDLINE, LILACS, BDENF, Scopus, Web of Science, EMBASE, and Science Direct.

The roles of periostin derived from cancer-associated fibroblasts in tumor progression and treatment response.

Periostin (POSTN), a matricellular protein predominantly secreted by cancer-associated fibroblasts (CAFs), has emerged as a key regulator of cancer progression and therapy response. This review provides an overview of recent findings regarding the diverse roles of periostin in cancer therapy and its potential as a therapeutic target. Studies have elucidated periostin's involvement in tumorigenesis, including tumor growth, metastasis, chemotherapy resistance, and modulation of the tumor microenvironment (TME).

Therapeutic efficacy of brown propolis from Araucaria sp. in modulating rheumatoid arthritis.

Rheumatoid arthritis is a systemic inflammatory autoimmune disease with prevalence estimated at 0.5% to 1% of the population. As one of the treatment routes of rheumatoid arthritis is based on the use of nonsteroidal anti-inflammatory drugs, the use of natural products with anti-inflammatory potential becomes relevant.