Publications by authors named "E F Legrottaglie"
Purpose: To evaluate the effectiveness of sequential custom phototherapeutic keratectomy (SCTK) for granular corneal dystrophy type 1 (GCD1).
Methods: Thirty-seven eyes of 21 patients with GCD1 were treated with SCTK to remove superficial opacifications, regularize the corneal surface, and decrease optical aberrations. SCTK is a sequence of custom therapeutic excimer laser keratectomies with step-by-step intraoperative corneal topography monitoring of results.
Purpose: To evaluate the repeatability of deformation corneal response (DCR) parameters before and after corneal crosslinking (CXL) compared with their untreated fellow eyes (uFEs).
Setting: University Hospital Carl Gustav Carus, Dresden, Germany; IRCCS Humanitas Research Hospital, Rozzano, Milan, Italy.
Design: Multicenter, interventional reliability analysis.
To report long-term clinical results of transepithelial cross-linking with iontophoresis (I-CXL) for progressive keratoconus (KC). Nineteen eyes of 19 patients treated with I-CXL for progressive keratoconus were included in this prospective clinical study. Preoperatively and in all available follow ups (6, 12, 24, 36, 48, 60, 72 and 84 months), the following parameters were measured.
View Article and Find Full Text PDFPurpose: To investigate if symptomatic conjunctivitis during the recovery phase of the disease could be associated to a persistent presence of SARS-CoV-2 in the upper respiratory tract. Secondary end points were to analyze the presence of SARS-CoV-2 in the conjunctiva of ocular symptomatic patients and to record the presence of ocular disturbances at this point of the disease.
Methods: An observational study including consecutive COVID19 patients treated at Humanitas Clinical and Research Hospital who were attending for nasopharyngeal swab to confirm the resolution of SARS-CoV-2 infection and end of isolation.
Article Synopsis
- The study evaluates the long-term safety and effectiveness of epithelium-off corneal cross-linking (S-CXL) in patients over 40 with progressive keratoconus, involving 76 eyes from 64 participants.
- Results show that S-CXL successfully halted disease progression in all patients and resulted in significant improvements in corneal shape and less visual distortion, with no need for repeat treatments.
- Although distance-corrected visual acuity remained stable over time, factors like atopy negatively impacted visual outcomes, indicating that while the procedure is generally effective, patient-specific conditions may affect results.