Publications by authors named "E F Asher"

Introduction: Cardiac troponin I is routinely measured in patients with suspected acute coronary syndrome. However, when a high-sensitivity cardiac troponin I (hs-cTnI) test is ordered without a clear clinical indication, unexpectedly elevated levels can lead to unnecessary diagnostic workups and inappropriate management. This study aimed to investigate physicians' rationale for performing hs-cTnI tests in an emergency department (ED).

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Article Synopsis
  • Platelets have a significant impact on aortic stenosis (AS) and patients undergoing transcatheter aortic valve implantation (TAVI), prompting an analysis of their indices in relation to AS stages.
  • In a study involving 220 TAVI patients, they were categorized into 5 AS stages based on cardiac damage, revealing a correlation between higher mean platelet volume (MPV) and advanced AS staging, as well as lower hemoglobin levels.
  • The findings indicate that while MPV and immature platelet fraction (IPF) show variations across stages, only MPV and body mass index (BMI) were significant predictors of higher AS staging in the logistic regression analysis.
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  • - The study investigates the relationship between peak high-sensitivity cardiac troponin (hs-cTn) levels and one-year mortality in patients admitted to intensive cardiovascular care units (ICCU) from 2019 to 2023.
  • - A total of 4149 patients were analyzed, revealing that those with hs-cTnI levels ≥100,000 ng/L had a significantly higher risk of mortality compared to lower levels, particularly in non-ST elevation myocardial infarction (NSTEMI) cases.
  • - The findings suggest that while high hs-cTnI levels indicate poor prognosis, the impact on mortality rates varies notably between patients with ST elevation myocardial infarction (STEMI) and NSTEMI, indicating a need
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