Publications by authors named "E Ebru Kovalak"

Background/aim: This study was designed to evaluate the relationship of two new biomarkers [tribbles homolog 3 (TRB3) and sestrin 2 levels], which were previously associated with obesity, with metabolic parameters in obese and nonobese women with polycystic ovary syndrome (PCOS).

Materials And Methods: This cross-sectional case control study was conducted between September 2017 and August 2019 in the gynecology department of a tertiary referral hospital. The values of the plasma sestrin 2, TRB3, insulin, fasting plasma glucose, lipid profile, and homeostasis model assessment of insulin resistance (HOMA-IR) were compared in 90 obese women with PCOS (BMI > 30), 90 women with nonobese PCOS (BMI < 30), and 90 control patients (BMI < 30).

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Objective: To present the laparoscopic management of heterotopic cesarean scar pregnancy and discuss other treatment options.

Design: Surgical video article. The Institutional Ethics Committee approved the video reproduction.

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Article Synopsis
  • The study aimed to assess new biomarkers for diagnosing and treating endometriosis in women with advanced stages of the disease compared to control patients.
  • The researchers compared various biomarkers in preoperative and postoperative serum samples, finding that only Ca-125 showed significant diagnostic value alone, with high sensitivity and specificity.
  • The combination of Ca-125 and Annexin A5 (ANXA5) demonstrated even greater diagnostic accuracy, suggesting it could be a more effective approach for identifying endometriosis.
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Background: Supracondylar humerus fractures (SCHFs) are the most common types of elbow fractures in children. Closed reduction percutaneous pinning (CRPP) is the primary surgical treatment of SCHFs. In cases that cannot be managed with closed reduction, treatment with open reduction and internal fixation (ORIF) is necessary.

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Objective: To determine the relationship between the cumulative effect of sequential clomiphene citrate (CC) treatments in unexplained infertile women with intercycle and intracycle serum hormone changes.

Materials And Methods: Patients who received CC 50 mg in the first cycle (group I, n=34) as ovulation induction and those who received CC 50 mg in the second consecutive cycle (group II, n=18) were compared. Basal (cycle days 2-5) and trigger day (the day that recombinant human chorionic gonadotropin is given) levels of gonadotropin and steroid hormones were measured.

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